Tissue ligation devices and tensioning devices therefor

A method of closing a target tissue comprising:

• advancing a closure device to a target tissue, the closure device comprising a snare loop, and a suture loop releasably coupled to the snare loop;
• advancing the closure device around the target tissue;
• applying a tension to the suture loop to release the suture loop from the snare loop;
• coupling a tail of the suture loop directly to a distal end of a tensioning device, wherein the tensioning device comprises a spring and a handle;
• pulling the tensioning device proximally relative to the closure device until a first predetermined force is applied to the suture loop, wherein the distal end of the tensioning device moves distally relative to the tensioning device handle during pulling;
• and
• pulling the tensioning device proximally relative to the closure device until a second predetermined force is applied to the suture loop.