Avocado flesh and/or skin extract rich in polyphenols and cosmetic, dermatological and nutraceutical compositions comprising same

A method for preventing and/or treating allergic, inflammatory or irritative reactions of the skin and/or mucous membranes and/or appendages, or for preventing and/or treating disorders or pathologies of the skin barrier, or homeostasis of the skin, comprising administering to a subject in need thereof an effective amount of a polyphenol-rich extract of avocado fruit, comprising at least 10% polyphenols by weight, expressed in gallic acid equivalents in relation to the dry extract, and comprising 0 to 10% by weight of avocado lipids in relation to the dry extract, wherein the polyphenols comprise a mixture of procyanidins, caffeic acid and derivatives of caffeic acid, wherein the mixture is at least 70% by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and wherein the mixture contains at least 20% caffeic acid and derivatives of caffeic acid and at least 30% procyanidins by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight,

• wherein said extract further comprises at least 10% avocado sugars by weight in relation to the weight of the dry extract, said sugars containing at least D-mannoheptulose and/or perseitol, and
• wherein said extract further comprises 1 to 30% avocado proteins by weight in relation to the weight of the dry extract.

A method for healing or depigmenting the skin and/or mucous membranes and/or appendages, comprising administering to a subject in need thereof an effective amount of a polyphenol-rich extract of avocado fruit, comprising at least 10% polyphenols by weight, expressed in gallic acid equivalents in relation to the dry extract, and comprising 0 to 10% by weight of avocado lipids in relation to the dry extract, wherein the polyphenols comprise a mixture of procyanidins, caffeic acid and derivatives of caffeic acid, wherein the mixture is at least 70% by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, wherein the mixture contains at least 20% caffeic acid and derivatives of caffeic acid and at least 30% procyanidins by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and

• wherein said extract further comprises at least 10% avocado sugars by weight in relation to the weight of the dry extract, said sugars containing at least D-mannoheptulose and/or perseitol, and
• wherein said extract further comprises 1 to 30% avocado proteins by weight in relation to the weight of the dry extract.

A method for preventing and/or treating vascular disorders, comprising administering to a subject in need thereof an effective amount of a polyphenol-rich extract of avocado fruit, comprising at least 10% polyphenols by weight, expressed in gallic acid equivalents in relation to the dry extract, and comprising 0 to 10% by weight of avocado lipids in relation to the dry extract, wherein the polyphenols comprise a mixture of procyanidins, caffeic acid and derivatives of caffeic acid, wherein the mixture is at least 70% by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and wherein the mixture contains at least 20% caffeic acid and derivatives of caffeic acid and at least 30% procyanidins by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and

• wherein said extract further comprises at least 10% avocado sugars by weight in relation to the weight of the dry extract, said sugars containing at least D-mannoheptulose and/or perseitol, and
• wherein said extract further comprises 1 to 30% avocado proteins by weight in relation to the weight of the dry extract.

A cosmetic care method for the skin and/or appendages and/or mucous membranes, for improving the condition and/or appearance of sensitive skin, or for preventing the accumulation of adipose tissue or skin with cellulitis, comprising administering to a subject in need thereof an effective amount of a polyphenol-rich extract of avocado fruit, comprising at least 10% polyphenols by weight, expressed in gallic acid equivalents in relation to the dry extract, and comprising 0 to 10% by weight of avocado lipids in relation to the dry extract, wherein the polyphenols comprise a mixture of procyanidins, caffeic acid and derivatives of caffeic acid, wherein the mixture is at least 70% by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and wherein the mixture contains at least 20% caffeic acid and derivatives of caffeic acid and at least 30% procyanidins by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and

• wherein said extract further comprises at least 10% avocado sugars by weight in relation to the weight of the dry extract, said sugars containing at least D-mannoheptulose and/or perseitol, and
• wherein said extract further comprises 1 to 30% avocado proteins by weight in relation to the weight of the dry extract.

A cosmetic care method for the skin and/or appendages and/or mucous membranes, for reducing pigmentation spots, comprising administering to a subject in need thereof an effective amount of a polyphenol-rich extract of avocado fruit, comprising at least 10% polyphenols by weight, expressed in gallic acid equivalents in relation to the dry extract, and comprising 0 to 10% by weight of avocado lipids in relation to the dry extract, wherein the polyphenols comprise a mixture of procyanidins, caffeic acid and derivatives of caffeic acid, wherein the mixture is at least 70% by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and wherein the mixture contains at least 20% caffeic acid and derivatives of caffeic acid and at least 30% procyanidins by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and

• wherein said extract further comprises at least 10% avocado sugars by weight in relation to the weight of the dry extract, said sugars containing at least D-mannoheptulose and/or perseitol, and
• wherein said extract further comprises 1 to 30% avocado proteins by weight in relation to the weight of the dry extract.

A cosmetic care method for preventing and/or treating ageing of the skin and/or the appendages and/or the mucous membranes, comprising administering to a subject in need thereof an effective amount of a polyphenol-rich extract of avocado fruit, comprising at least 10% polyphenols by weight, expressed in gallic acid equivalents in relation to the dry extract, and comprising 0 to 10% by weight of avocado lipids in relation to the dry extract, wherein the polyphenols comprise a mixture of procyanidins, caffeic acid and derivatives of caffeic acid, wherein the mixture is at least 70% by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and wherein the mixture contains at least 20% caffeic acid and derivatives of caffeic acid and at least 30% procyanidins by weight, expressed in gallic acid equivalents, in relation to total polyphenol content by weight, and

• wherein said extract further comprises at least 10% avocado sugars by weight in relation to the weight of the dry extract, said sugars containing at least D-mannoheptulose and/or perseitol, and
• wherein said extract further comprises 1 to 30% avocado proteins by weight in relation to the weight of the dry extract.