Barley and uses thereof
AssigneeThe Healthy Grain Pty Limited
InventorsZhongyi Li, Matthew Kennedy Morell
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AssigneeThe Healthy Grain Pty Limited
InventorsZhongyi Li, Matthew Kennedy Morell
Estimating the term…
The invention provides barley grain comprising a reduced level or activity of starch synthase IIa protein and a starch content of at least 41% (w/w) and methods of producing, identifying and using same. The grain may comprise an amylase content of at least 50%, a β-glucan content of 5-9% (w/w) or greater than 9% (w/w), and/or a fructan content of 3-11% (w/w). The fructan may comprise a degree of polymerization from about 3 to about 12. For example, the plant and grain comprises a sex6-292 allele and/or an amo1 mutation. A food or beverage product, and methods of producing a food or beverage product, comprising obtaining or producing the subject grain and processing the grain to produce the product. Also contemplated are methods of improving one or more indicators of health in a mammal comprising administering a composition comprising the subject barley grain or a product comprising same.
A method for providing starch to improve one or more indicators of health in a human, wherein the method comprises administering, to the human, a composition comprising barley grain, or wholemeal or flour obtained from barley grain, wherein the barley grain comprises (i) a loss of function mutation in an endogenous gene encoding starch synthase IIa (SSIIa), and (ii) an amo1-AC38 allele, wherein the barley grain is homozygous for the loss of function mutation in the endogenous gene encoding SSIIa and for the amo1-AC38 allele, and the barley grain lacks detectable SSIIa protein in endosperm of the grain.
A method for providing starch, amylose, amylopectin, β-glucan, fructan, non-starch polysaccharide, dietary fibre or resistant starch to a mammal, wherein the method comprises administering, to the mammal, a composition comprising barley grain, or wholemeal or flour obtained from the barley grain, wherein the barley grain comprises (i) a loss of function mutation in an endogenous gene encoding starch synthase IIa (SSIIa), and (ii) an amo1-AC38 allele, wherein the barley grain is homozygous for the loss of function mutation in the endogenous gene encoding SSIIa and for the amo1-AC38 allele, and the barley grain lacks detectable SSIIa protein in endosperm of the grain, wherein the composition has a reduced glycaemic index relative to a composition comprising wild-type barley grain or wholemeal or flour obtained from wild-type barley grain.
Dependencies are inferred from the claim text.