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US 10,946,109 B2Granted
Polymer-type fluorescent molecule probe
AssigneeHiroshi Maeda
InventorsHiroshi Maeda, Makoto Hashizume, Jun Fang, Hideaki Nakamura, Haibo Qin, Steffen Hackbarth, Masaharu Murata
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Abstract
The present invention provides a fluorescent molecular probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic treatment, more specifically, the present invention provides a macromolecular fluorescent molecular probe for fluorescent detection of tumor, comprising a complex comprising a fluorescent molecule and a biocompatible macromolecule.
Claims6
A complex comprising a fluorescent molecule and a biocompatible macromolecule,
- wherein the fluorescent molecule is chlorophyll,
- the biocompatible macromolecule is selected from styrene-maleic acid copolymers, styrene-maleic acid copolymers having a multiple-functionalized maleic acid side chain, and mixtures thereof,
- the fluorescent molecule is non-covalently bound to the biocompatible macromolecule, and
- the complex is in the form of a micelle in which the fluorescent molecule is encapsulated in the biocompatible macromolecule.
1 more element
Dependencies are inferred from the claim text.