IL-2 muteins and uses thereof
AssigneePandion Operations, Inc.
InventorsNathan Higginson-Scott, Joanne L. Viney, Jyothsna Visweswaraiah, Erik Robert Sampson, Kevin Lewis Otipoby
Life of this patent
Estimating the term…
Abstract
The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.
Claims27
A method of increasing I regulatory cell proliferation in a subject, the method comprising administering to the subject an effective amount of a pharmaceutical composition comprising a peptide comprising the amino acid sequence of SEQ ID NO:
- 26 wherein the I regulatory cell proliferation is increased in the subject.
A method of activating T regulatory cells in a subject, the method comprising administering to the subject an effective amount of a pharmaceutical composition comprising a peptide comprising the amino acid sequence of SEQ ID NO:
- 26, wherein the I regulatory cells are activated in the subject.
Dependencies are inferred from the claim text.