Pharmaceutical suspension dosage form of benzimidazole compounds and process of preparation thereof

A solid oral dosage form consisting of enteric coated pellets of esomeprazole magnesium and a suspension modifying inactive granulate, wherein:

• the enteric coated pellets of esomeprazole magnesium consist of:
• 18.78% (w/w) of sugar spheres coated with a first layer, a second layer and an outermost third layer, and the first layer consists of 25.11% (w/w) esomeprazole magnesium, 1.7% (w/w) hydroxypropylmethyl cellulose and 0.5% (w/w) polysorbate 80;
• the second layer consists of 9.03% (w/w) hydroxypropyl cellulose, 1.23% (w/w) magnesium stearate and 17.08% (w/w) talc over the first layer;
• and the third outermost layer consists of 23.74% (w/w) methacrylic acid copolymer, 1.23% (w/w) glycerol monostearate, 0.13% (w/w) polysorbate 80 and 1.47% (w/w) triethyl citrate over the second layer, wherein the weight percentages are of the enteric coated pellets;
• and
• the suspension modifying inactive granulate consists of 94.87% (w/w) dextrose, 2.5% (w/w) xanthan gum, 2.5% (w/w) crospovidone, 0.08% (w/w) citric acid and 0.05% (w/w) iron oxide, wherein the weight percentages are of the granulate.