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US 10,945,995 B2Granted
Compositions and methods for channelopathy disorders-targeting fluid movement across membranes
AssigneeDeha, LLC
InventorsKumar Sripathirathan, Adhya Kumar
Life of this patent
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Abstract
The present invention includes composition and methods for treating stroke comprising: identifying a subject in need of treatment for a stroke; and providing the subject with a therapeutically effective amount of an Aquaporin-4 inhibitor that blocks a filter portion of an Aquaporin-4 channel region, and identifying modulators of the different aquaporin specific splice variants.
Claims8
A method of treating a subject in need of treatment for a disease or condition in which an Aquaporin-2, an Aquaporin-4, an Aquaporin-6, or an Aquaporin-11 is in need of modulation comprising:
- providing the subject with a therapeutically effective amount of an Aquaporin-2, an Aquaporin-4, an Aquaporin-6, or an Aquaporin-11, inhibitor or modulator selected from at least one of:
Dependencies are inferred from the claim text.