Magnetic resonance fingerprinting optimization in magnetic resonance imaging

A method for determining a configuration for a magnetic resonance scanner using magnetic resonance fingerprinting, the method comprising:

• generating a first image fingerprint from magnetic resonance corresponding to a first sequence and a plurality of ground truth values of magnetic resonance output parameters;
• transforming the first image fingerprint to k-space;
• applying a first sampling pattern to the transformed first image fingerprint;
• reconstructing first values of the magnetic resonance output parameters from results of the applying of the first sampling pattern, the reconstructing using a first reconstruction setting;
• scoring the first values with respect to the ground truth values;
• optimizing the scoring based on repetition of the generating with different sequences than the first sequence, transforming, applying with different sampling patterns than the first sampling pattern, and reconstructing with different reconstructing settings;
• selecting a magnetic resonance fingerprinting sequence from the first and different sequences, a magnetic resonance fingerprinting sampling pattern from the first and different sampling patterns, and a magnetic resonance fingerprinting reconstruction setting from the first and different reconstruction settings;
• and
• providing the selected magnetic resonance fingerprinting sequence, sampling pattern, and reconstruction setting for the magnetic resonance scanner.