US 10,870,841 B1Granted

Nucleic acid-guided nucleases

AssigneeInscripta, Inc.

InventorsBenjamin Mijts, Aamir Mir, Andrew Garst, Juhan Kim, Kyle Seamon

Life of this patent

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Abstract

The present disclosure provides novel RNA-guided enzymes for making rational and direct edits to the genome of live cells.

Claims10

Dependent claims

A coding sequence for a nucleic acid-guided nuclease comprising a nucleic acid sequence of any of SEQ ID Nos. 6, 13 or 18.

Dependencies are inferred from the claim text.

Facts

Application: 16/988,690Filed 9 Aug 2020 · continuation
Priority: 13 Dec 2019
Granted: 22 Dec 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

C12N 9/22
Acting on ester bonds: ribonucleases [RNase]; Deoxyribonucleases [DNase]
C12N 9/222
Ribonucleases [RNase]; Deoxyribonucleases [DNase]: clustered regularly interspaced short palindromic repeats [CRISPR]-associated [CAS] enzymes
C12N 15/102
Processes for the isolation, preparation or purification of DNA or RNA: mutagenizing nucleic acids
C12N 15/70
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression: vectors or expression systems…

Family

Application16/714,320Parent of this continuation · filed 13 Dec 2019
Application16/868,472Parent of this continuation · filed 6 May 2020
US 10,704,033 B1Parent of this continuation · filed 7 Jul 2020
Application16/928,742Parent of this continuation · filed 14 Jul 2020
US 10,724,021 B1Parent of this continuation · filed 28 Jul 2020
US 10,767,169 B1Parent of this continuation
US 10,870,841 B1This patent

From the US filing history. Foreign family members aren’t listed.

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