Compositions and methods comprising a lipolytic enzyme variant
AssigneeDanisco US Inc.
InventorsThomas P. Graycar, Ayrookaran J. Poulose, David A. Estell
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Abstract
The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
Claims16
A lipolytic enzyme variant or an active fragment thereof comprising an amino acid substitution at a position 187, wherein the lipolytic enzyme variant has at least 85% sequence identity to SEQ ID NO:
- 1 and the amino acid positions of the variant are numbered by correspondence with the amino acid sequence of Thermomyces lanuginosa lipase set forth in SEQ ID NO:
- 1, and wherein the amino acid substitution is selected from the group consisting of V187N, V187H, V187Q and V187T.
Dependencies are inferred from the claim text.