Organic anion lithium ionic cocrystal compounds and compositions
AssigneeUniversity of South Florida
InventorsMichael John Zaworotko, Naga Duggirala, Adam John Smith, Roland Douglas Shytle
Life of this patent
Estimating the term…
Abstract
A cocrystal having the formula LiX.aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical compositions comprising such cocrystals, cocrystal solvates, or cocrystal hydrates, and methods of preparing such cocrystals, cocrystal solvates, or cocrystal hydrates, and such pharmaceutical compositions.
Claims19
A method of preparing a pharmaceutical composition containing a lithium cocrystal composition, the method comprising combining the lithium cocrystal composition with a pharmaceutically acceptable carrier or diluent, wherein the lithium cocrystal composition is produced by (1) mixing (i) a lithium salt comprising a conjugate base of an organic acid and (ii) a complementary neutral organic molecule in a solvent and (2) evaporating or cooling the solvent to form the lithium ionic cocrystal composition.
Dependencies are inferred from the claim text.