US 10,870,620 B1 · Radioactive carbon-14-labeled 2,2′-(((4-((4-14C chlorobenzyl)oxy)-3-methoxyphenyl)methylene)bis(2-hydroxyethyl)dithioacetal, preparation method and applications there of

Abstract

The present disclosure provides a radioactive carbon-14 labeled XCLSBM in the structure of Formula 4 and its preparation method and applications. A 14C labeled raw material is used to synthesize a 14C-labeled XCLSBM, and a method for synthesizing a trace 14C-labeled marker of 14C-labeled XCLSBM is established, which avoids high-temperature, high-pressure reactions and the production process is safe with a low synthesis cost. The radioactive carbon-14 labeled XCLSBM can be used to trace the migration and transformation, metabolic degradation, absorption and enrichment of XCLSBM in environment and living bodies, for providing technical supports for comprehensive evaluation of the ecological safety of XCLSBM.

Claims10

Dependent claims

A radioactive carbon-14-labeled XCLSBM, characterized in that the chemical name is 2,2′-(((4-(4-14C chlorobenzyl)oxy)-3-methoxyphenyl)methylene)bis (2-hydroxyethyl) dithioacetal, the structural formula is shown as Formula 4:

wherein the asterisk represents the position of the carbon-14 mark.

Dependencies are inferred from the claim text.

Facts

Application

16/935,727Filed 22 Jul 2020

Priority

CN 2019 1 066682823 Jul 2019

Granted

22 Dec 2020

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07C 323/16
Having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton: the carbon skeleton containing six-membered…
C07B 59/001
Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se: acyclic or carbocyclic compounds
C07C 17/16
By replacement by halogens: of hydroxyl groups
C07C 29/147
Of >C=O containing groups, e.g. —COOH: of carboxylic acids or derivatives thereof

Radioactive carbon-14-labeled 2,2′-(((4-((4-14C chlorobenzyl)oxy)-3-methoxyphenyl)methylene)bis(2-hydroxyethyl)dithioacetal, preparation method and applications there of

Life of this patent

Radioactive carbon-14-labeled 2,2′-(((4-((4-14C chlorobenzyl)oxy)-3-methoxyphenyl)methylene)bis(2-hydroxyethyl)dithioacetal, preparation method and applications there of

Life of this patent

Abstract

Claims10