Method and apparatus for sequential deployment of intra-tumoral agents

An apparatus for sequential deployment of intra-tumoral agents, said apparatus comprising:

• an elongated shaft assembly including:
• a distal end portion with at least one port opening;
• at least a first and second lumen axially disposed within the elongated shaft assembly, the at least first and second lumen extending through the shaft and engaged to the at least one port opening at the distal end, wherein the first lumen comprises a therapeutic agent for deployment and the second lumen comprises a binding agent for subsequent deployment;
• an intra-tumoral probe wire slidably interposed there between or slidably disposed between any one of, or combination of the at least first and second lumen;
• a proximal end housing a finger-led control coupled to an actuator, whereby said actuator is in operable communication to any one of, or combination of, the at least one port opening, protraction, retraction, and deployment of the intra-tumoral probe wire and, or a deployment line fittingly disposed between and, or within any of the at least first and second lumen, said deployment line operably coupled to and causing displacement of any one of an agent, at least one port, and, or intra-tumoral probe wire;
• and
• wherein the displacement of the intra-tumoral probe wire interposed there between or slidably disposed between any one of, or combination of, the at least first and second lumen causes disruption of a tumor tissue and forms an inlet for displacement of a first agent comprising any one of a therapeutic agent from the first lumen and a subsequently deployed second agent comprising any one of a binding agent from the second lumen, wherein the binding agent encapsulates and/or calcifies the tumor for prolonged exposure of the tumor to the therapeutic agent.