US 10,869,934 B2Granted

Antiproliferative compounds and conjugates made therefrom

AssigneeBristol-Myers Squibb Company

InventorsIvar M. McDonald, Prasanna Sivaprakasam, Christiana I. Iwuagwu, Kevin M. Peese, Heng Cheng, Naidu S. Chowdari, Sanjeev Gangwar

Life of this patent

Estimating the term…

Abstract

A compound capable of inhibiting cell proliferation, having a structure according to formula (I) wherein the variables in formula (I) are as defined in the specification. Such compounds are useful as anti-cancer agents, especially in antibody-drug conjugates.

Claims1

Dependent claims

A compound having a structure according to formula (Ib-54)

Dependencies are inferred from the claim text.

Facts

Application: 16/533,226Filed 6 Aug 2019 · continuation
Priority: 20 Oct 2016
Published: US 2019/0358339 A128 Nov 2019
Granted: 22 Dec 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

C07D 471/04
In which the condensed system contains two hetero rings: ortho-condensed systems
A61K 47/6803
Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent: drugs conjugated to an antibody or…
A61P 35/00
Antineoplastic agents
C07D 519/00
Heterocyclic compounds containing more than one system of two or more relevant

Family

Application62/410,624Us provisional application · filed 20 Oct 2016
Application15/789,027Parent of this continuation · filed 20 Oct 2017
US 2019/0358339 A1Pre-grant publication · published 28 Nov 2019
US 10,398,783 B2Parent of this continuation
US 2018/0110873 A1Published application
US 10,869,934 B2This patent

From the US filing history. Foreign family members aren’t listed.

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