Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
AssigneeEvelo Biosciences, Inc.
InventorsDavid Berry, Noubar B. Afeyan, Johanne Kaplan, Neal Gordon, Shaila Rahman
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Abstract
Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
Claims7
A method of reducing inflammation in the gastrointestinal tract of a subject, comprising orally administering to the subject a composition comprising an isolated population of bacteria of the genus Blautia, such that inflammation in the gastrointestinal tract of the subject is reduced.
Dependencies are inferred from the claim text.