Back to results
US 10,869,848 B2Granted
Carmustine pharmaceutical composition
AssigneeNavinta III Inc
InventorMahendra R. Patel
Life of this patent
Estimating the term…
Abstract
The present invention provides pharmaceutical formulations of lyophilized carmustine suitable for pharmaceutical use. The present invention further provides methods of producing lyophilized carmustine. The pharmaceutical formulations can be used for any disease that is sensitive to treatment with carmustine, such as neoplastic diseases.
Claims17
A process of preparing a lyophilized carmustine pharmaceutical composition comprising the steps of:
- (a) dissolving 3-400 mg/mL carmustine in a solvent consisting essentially of dehydrated t-butanol a second and dehydrated alcohol to obtain a carmustine solution,
- (b) freezing the carmustine solution of step (a), and
- (c) removing the dehydrated t-butanol and dehydrated alcohol at a first freeze-drying temperature after the step (b) of freezing.
Dependencies are inferred from the claim text.