Back to results
US 10,869,833 B2Granted
Drug delivery devices for delivery of ocular therapeutic agents
OwnerCasey Kopczynski, Cheng-Wen Lin +1inventors
InventorsCasey Kopczynski, Cheng-Wen Lin, Chris Sutay
Life of this patent
Estimating the term…
Abstract
Drug delivery devices comprising a non-bioabsorbable polymer structure configured to support a composition comprising an active agent. The devices include a plurality of portions fused together and a recess configured to support the composition. At least one of the portions includes an impermeable polymer and at least one other portion includes a rate-limiting water-permeable polymer. The rate-limiting water-permeable polymer allows for transportation of the active agent to an exterior of the device.
Claims14
A device for insert in the eye, the device comprising:
- a first portion comprising a rate-limiting water-permeable polymer;
- a second portion fused to the first portion, the second portion including a composition comprising latanoprost free acid salt as an active agent;
- and
- a third portion fused to the second portion, the third portion comprising a rate-limiting water-permeable polymer,
- wherein the rate-limiting water-permeable polymer allows for transportation of the active agent to an exterior of the device and wherein the rate-limiting water-permeable polymer is configured to release the latanoprost free acid salt at a rate of 0.00025 to 0.0075 μg/h when the drug delivery device is to be placed episclerally or at a rate of 0.0005 to 0.015 μg/h when the drug delivery device is to be placed supraconjunctivally, and
- wherein the device is configured to release 70% to 90% of the latanoprost free acid salt over a period of at least 30 days.
3 more elements
Dependencies are inferred from the claim text.