Systems and methods for heart valve therapy

A prosthetic mitral valve system comprising:

• an anchor assembly comprising an expandable anchor frame and a prosthetic element attached to the expandable anchor frame, the anchor assembly coupleable with a native mitral valve having an anterior leaflet and a posterior leaflet that cycle between an open valve orientation and a closed valve orientation in which free edges of the anterior and posterior leaflets oppose each other to define a coaptation line,
• wherein while the anchor assembly is coupled with the native mitral valve:
• (i) the anterior and posterior leaflets continue to cycle between the open valve orientation and the closed valve orientation in which the free edges of the anterior and posterior leaflets oppose each other to define the coaptation line, (ii) at least a portion of the prosthetic element is positioned along the coaptation line between the free edges of the anterior and posterior leaflets while the anterior and posterior leaflets are in the closed valve orientation and (iii) the prosthetic element functions as a prosthetic leaflet that cycles between the open valve orientation and the closed valve orientation;
• and
• a valve assembly comprising an expandable valve frame and an occluder attached to the expandable valve frame, the valve assembly selectively coupleable with the anchor assembly.