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US 10,869,719 B2Granted
Pulsed radiofrequency ablation
AssigneeAffera, Inc.
InventorsDoron Harlev, Andrew Miles Wallace, Luke Tsai
Life of this patent
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Abstract
Ablation systems and methods of the present disclosure are directed toward delivering pulsed radiofrequency (RF) energy to target tissue. The pulsations of the RF energy, combined with cooling at a surface of the target tissue, can advantageously promote local heat transfer in the target tissue to form lesions having dimensions larger than those that can be safely formed in tissue using non-pulsed RF energy under similar conditions.
Claims19
A method comprising:
- placing an expandable ablation electrode at an interface between tissue and blood in an anatomic structure of a patient, wherein the expandable ablation electrode is at a distal end portion of a catheter shaft and surrounds an irrigation port configured to direct irrigation fluid toward the interface, and wherein the irrigation port is coupled to the distal end portion of the catheter shaft at only a proximal end portion of the irrigation port;
- delivering electrical energy to the ablation electrode at the interface during a period of lesion formation;
- receiving, from a temperature sensor disposed at the interface, a signal indicative of temperature of the interface;
- and
- delivering the irrigation fluid to the interface via the irrigation port during at least a portion of the period of lesion formation,
- wherein—
- the electrical energy delivered to the ablation electrode at the interface is changed between a first energy phase and a second energy phase during the period of lesion formation,
- the electrical energy delivered in the first energy phase is greater than the electrical energy delivered in the second energy phase,
- a combination of irrigation fluid and blood moves through the ablation electrode to cool the temperature of the interface during the period of lesion formation.
6 more elements
A method comprising:
- positioning an expandable ablation electrode at an interface between tissue and blood in an anatomic structure of a patient, wherein the expandable ablation electrode is carried b a catheter shaft and surrounds an irrigation port configured to direct irrigation fluid toward the interface, and wherein the irrigation port is coupled to a distal end region of the catheter shaft at only a proximal end region of the irrigation port;
- delivering electrical energy to the ablation electrode at the interface;
- receiving, from a temperature sensor disposed at the interface, a signal indicative of temperature of the interface;
- and
- delivering the irrigation fluid to the interface via the irrigation port during at least a portion of the period of lesion formation,
- wherein—
- the electrical energy delivered to the ablation electrode at the interface is changed between a first energy phase and a second energy phase during the period of lesion formation,
- the electrical energy in the first energy phase is greater than the electrical energy delivered in the second energy phase,
- a combination of irrigation fluid and blood moves across the interface to cool the temperature of the interface during the period of lesion formation.
6 more elements
A method comprising:
- placing an expandable ablation electrode at an interface between tissue and blood in an anatomic structure of a patient, wherein the expandable ablation electrode is at a distal portion of a catheter shaft and surrounds an irrigation port configured to direct irrigation fluid toward the interface, and further wherein the irrigation port is connected to the distal portion of the catheter shaft at only a proximal end portion of the irritation port;
- delivering electrical energy to the ablation electrode at the interface during a period of lesion formation;
- receiving, from a temperature sensor disposed at the interface, a signal indicative of temperature of the interface;
- and
- delivering the irrigation fluid to the interface via the irrigation port during at least a portion of the period of lesion formation,
- wherein—
- the electrical energy delivered to the ablation electrode at the interface is changed between a first energy phase and a second energy phase during the period of lesion formation,
- the electrical energy delivered in the first energy phase is greater than the electrical energy delivered in the second energy phase,
- a duration of the first energy phase is less than a duration of the second energy phase, and
- a combination of irrigation fluid and blood moves through the ablation electrode to cool the temperature of the interface during the period of lesion formation.
7 more elements
Dependencies are inferred from the claim text.