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US 10,869,718 B2Granted
Methods and systems for treating diabetes and related diseases and disorders
AssigneeFractyl Laboratories, Inc.
InventorsHarith Rajagopalan, Jay Caplan, Craig M. Gardner, J. Christopher Flaherty
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Abstract
Systems, device and methods treat target tissue to provide a therapeutic benefit to the patient. A tissue treatment device comprises a tissue treatment element constructed and arranged to treat target tissue, such as duodenal mucosa tissue.
Claims18
A method of treating target tissue to provide a therapeutic benefit to a patient with type 2 diabetes, the method comprising:
- providing a tissue treatment device comprising a tissue treatment element constructed and arranged to treat target tissue by ablation, wherein the target tissue comprises at least duodenal mucosal tissue;
- advancing the tissue treatment device into the intestine of the patient;
- and
- treating a cumulative length of at least 4 cm but less than all of duodenal mucosal tissue to provide the therapeutic benefit to the patient, wherein treating comprises ablating the duodenal mucosal tissue;
- wherein the treated cumulative length of duodenal mucosal tissue has a proximal most edge which is located in a region between 1 cm distal to the ampulla of Vater and 3 cm distal to the ampulla of Vater.
2 more elements
The method according to 1, wherein the cumulative length is treated by performing three or more ablations of the duodenum.
Dependencies are inferred from the claim text.