Peptide showing melanogenesis promoting activity and use thereof
AssigneeCaregen Co., Ltd.
InventorsYong Ji Chung, Eun Mi Kim, Eung-Ji Lee
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Abstract
Peptides exhibiting melanogenesis promoting activity are described. The peptides increase the activity and expression of tyrosinase and the expression of factors involved in melanogenesis, thereby exhibiting an outstanding effect on melanogenesis. The peptides can be used for the prevention, alleviation, and treatment of hypomelanosis. The outstanding activity and stability stated above allow the peptides to be very favorably applied to medicines, quasi-medicines, and cosmetics.
Claims20
A peptide consisting of the amino acid sequence SEQ ID NO:
- 2 or SEQ ID NO:
- 3, wherein (i) the C-terminal end of the peptide is modified by the presence of an amino group or an azide group, or (ii) the N-terminal end of the peptide comprises a protecting group.
A pharmaceutical composition for the treatment of hypomelanosis, comprising, as an active ingredient, at least one peptide selected from the group consisting of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 2 and a peptide consisting of the amino acid sequence of SEQ ID NO:
- 3, optionally wherein (i) the C-terminal end of the peptide is modified by the presence of an amino group or an azide group, or (ii) the N-terminal end of the peptide comprises a protecting group.
A cosmetic composition for the alleviation of hypomelanosis, comprising, as an active ingredient, at least one peptide selected from the group consisting of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 2 and a peptide consisting of the amino acid sequence of SEQ ID NO:
- 3, optionally wherein (i) the C-terminal end of the peptide is modified by the presence of an amino group or an azide group, or (ii) the N-terminal end of the peptide comprises a protecting group.
Dependencies are inferred from the claim text.