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US 10,865,198 B2Granted
Solid forms of cerdulatinib
AssigneeAlexion Pharmaceuticals, Inc.
InventorsAnjali Pandey, Julian Scott Northen, Philippe Fernandes, Ying Chen, Yuelie Lu, Sami Karaborni, Gus Kodersha
Life of this patent
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Abstract
Forms of cerdulatinib and salts or co-crystals thereof were prepared and characterized in the solid state. Also provided are processes of manufacture and methods of using the forms cerdulatinib and salts or co-crystals thereof.
Claims40
A crystalline mono-hydrochloride salt of Compound I:
- characterized by an X-ray powder diffractogram comprising peaks at 8.7, 15.9, and 20.0°2θ, each ±0.2°2θ, as determined on a diffractometer using Cu-Kα radiation (Compound I HCl Form I).
A crystalline hydrochloride salt of Compound I:
- characterized by an X-ray powder diffractogram comprising peaks at 7.9, 19.6, and 13.3°2θ, each ±0.2°2θ, as determined on a diffractometer using Cu-Kα radiation (Compound I HCl Type B).
Dependencies are inferred from the claim text.