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AssigneeRoche Diagnostics Operations, Inc.
InventorsThorsten Brueckner, Nadine Losleben, Norbert Oranth
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A method of dispensing a particle mixture and a reagent fluid cartridge are presented. The cartridge comprises a first reservoir partially filled with reagent fluid, a second reservoir partially filled with particles, a pumping chamber, a first pumping chamber conduit connecting the first reservoir and the pumping chamber, a second pumping chamber conduit connecting the second reservoir and the pumping chamber, an outlet for dispensing reagent fluid and particles from the cartridge, an outlet conduit connecting the outlet to the pumping chamber, and a valve sealing the outlet conduit. The method comprises closing the valve, applying a force to the plunger to transport a first defined volume of reagent fluid and second defined volume of particles into the pumping chamber to form a mixture of reagent fluid and particles, opening the valve, and forcing the mixture from the pumping chamber using the plunger to dispense the mixture from the outlet.
A method of performing a measurement on a sample containing an analyte using a cartridge, wherein the cartridge comprises a first reservoir at least partially filled with a reagent fluid, a second reservoir at least partially filled with particles, a pumping chamber, wherein the pumping chamber is formed from a cavity, wherein the cartridge further comprises a plunger mounted within the pumping chamber, wherein the plunger is configured for changing the volume of the pumping chamber, wherein the cartridge further comprises at least one first pumping chamber conduit connecting the first reservoir and the pumping chamber, at least one second pumping chamber conduit connecting the second reservoir and the pumping chamber, an outlet for dispensing the reagent fluid and the particles from the cartridge, an outlet conduit connecting the outlet to the pumping chamber, and a valve for sealing the outlet conduit, wherein a fluid conductivity of the outlet conduit is larger than a fluid conductivity of the at least one first pumping chamber conduit and a fluid conductivity of the at least one second pumping chamber conduit, the method comprising:
A cartridge for an automatic analyzer, the cartridge comprising:
A method of dispensing a mixture of particles and reagent fluid using a cartridge, wherein the cartridge comprises a first reservoir at least partially filled with a reagent fluid, a second reservoir at least partially filled with particles, a pumping chamber, wherein the pumping chamber is formed from a cavity, wherein the cartridge further comprises a plunger mounted within the pumping chamber, wherein the plunger is configured for changing the volume of the pumping chamber, wherein applying a force to transport a first defined volume of reagent fluid and a second defined volume of particles into the pumping chamber to form a mixture of reagent fluid and particles comprises expanding the volume of the pumping chamber with the plunger, and wherein forcing the mixture in the pumping chamber to dispense the mixture comprises reducing the volume of the pumping chamber with the plunger, at least one first pumping chamber conduit connecting the first reservoir and the pumping chamber, at least one second pumping chamber conduit connecting the second reservoir and the pumping chamber, an outlet for dispensing the reagent fluid and the particles from the cartridge, an outlet conduit connecting the outlet to the pumping chamber, and a valve for sealing the outlet conduit, wherein a fluid conductivity of the outlet conduit is larger than a fluid conductivity of the at least one first pumping chamber conduit and a fluid conductivity of the at least one second pumping chamber conduit, the method comprising:
Dependencies are inferred from the claim text.