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US 10,864,374 B2Granted
Transvascular nerve stimulation apparatus and methods
AssigneeLungpacer Medical Inc.
InventorJoaquin Andres Hoffer
Life of this patent
Estimating the term…
Abstract
Electrode structures for transvascular nerve stimulation combine electrodes with an electrically-insulating backing layer. The backing layer increases the electrical impedance of electrical paths through blood in a lumen of a blood vessel and consequently increases the flow of electrical current through surrounding tissues. The electrode structures may be applied to stimulate nerves such as the phrenic vagus, trigeminal, obturator or other nerves.
Claims16
A system for stimulating a nerve in a patient, comprising:
- an electrode structure supported on a flexible electrically insulating sheet, the electrode structure comprising a plurality of electrodes, wherein the plurality of electrodes comprise a first electrode and a second electrode, and wherein the first electrode is positionable proximate a left phrenic nerve, and the second electrode is positionable proximate a right phrenic nerve, and the first electrode is configured to stimulate the left phrenic nerve and the second electrode is configured to stimulate the right phrenic nerve;
- and
- a tube configured for intravascular insertion, wherein the electrode structure and at least a first portion of the electrically insulating sheet are spirally arranged on the tube, and the plurality of the electrodes comprise an array of electrodes aligned longitudinally with respect to the tube;
- wherein the flexible electrically insulating sheet includes:
- a proximal end in contact with the tube;
- a distal end in contact with the tube;
- and
- a segment that supports an electrode of the plurality of electrodes, wherein the segment is between the proximal end of the flexible electrically insulating sheet and the distal end of the flexible electrically insulating sheet, and is in contact with the tube when the system delivers stimulation.
5 more elements
A system for stimulating a nerve in a patient, comprising:
- an electrode structure supported on a flexible electrically insulating sheet, wherein the electrode structure comprises a plurality of electrodes, and at least one electrode of the plurality of electrodes is configured to stimulate the nerve;
- and
- a tube configured for intravascular insertion, wherein the electrode structure is spirally arranged on the tube so that a first electrode of the plurality of electrodes is longitudinally and circumferentially spaced from a second electrode of the plurality of electrodes;
- wherein the flexible electrically insulating sheet includes:
- a proximal end in contact with the tube;
- a distal end in contact with the tube;
- and
- a segment that supports at least two electrodes of the plurality of electrodes, wherein the segment is between the proximal end of the flexible electrically insulating sheet and the distal end of the flexible electrically insulating sheet, and is in contact with the tube when the system delivers stimulation, and
- when the system delivers stimulation, the flexible electrically insulating sheet is spirally arranged so that each of the plurality of electrodes faces radially outward.
6 more elements
A system for stimulating a nerve in a patient, comprising:
- a plurality of electrodes supported on a flexible electrically insulating sheet, wherein at least one electrode of the plurality of electrodes is configured to stimulate the nerve;
- and
- a plurality of leads arranged longitudinally along the electrically insulating sheet, each of the plurality of leads being configured to provide a stimulation signal to a corresponding one of the plurality of electrodes,
- wherein the electrically insulating sheet is spirally arranged on the tube so that each of the plurality of electrodes faces radially outward and not radially inward, and wherein the plurality of electrodes comprise an array of longitudinally and circumferentially spaced electrodes;
- and
- wherein the flexible electrically insulating sheet includes:
- a proximal end in contact with the tube;
- a distal end in contact with the tube;
- and
- a segment that supports at least two electrodes of the plurality of electrodes, wherein the segment is between the proximal end of the flexible electrically insulating sheet and the distal end of the flexible electrically insulating sheet, and is in contact with the tube when the system delivers stimulation, and
- when the system delivers stimulation, the flexible electrically insulating sheet is spirally arranged so that each of the plurality of electrodes faces radially outward.
8 more elements
Dependencies are inferred from the claim text.