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AssigneeThe Board of Trustees of the University of Illinois
InventorsJoseph D. Donovan, Soo-Yeun Lee, Youngsoo Lee
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The invention provides novel formulations comprising a stable inclusion complex of tributyrin and a cyclodextrin. In one particular embodiment, the formulation comprises an oven dried inclusion complex of tributyrin and γ-cyclodextrin that is effective in minimizing or preventing the unpleasant taste and odor of tributyrin, thus making it suitable for oral administration and delivery to the digestive tract and intestines. The invention provides compositions of these inclusion complexes and methods of using them that are advantageous as food, medicinal and other products, where the negative sensory properties of tributyrin can be a liability.
A stable inclusion complex comprising tributyrin and γ-cyclodextrin, wherein the molar ratio of tributyrin to γ-cyclodextrin consists of about 1:1 to about 1:3 and the inclusion complex is olfactorily and gustorialy neutral in comparison to free tributyrin wherein tributyrin is encapsulated by γ-cyclodextrin to form a solid inclusion complex.
A stable inclusion complex comprising tributyrin and γ-cyclodextrin, wherein the molar ratio of tributyrin to γ-cyclodextrin is about 1:1 to about 1:3 and the inclusion complex is olfactorily and gustorialy neutral in comparison to free tributyrin wherein the inclusion complex is oven dried.
Dependencies are inferred from the claim text.