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US 10,864,224 B2Granted
Synthetic composition for treating antibiotic associated complications
AssigneeGlycom A/S
InventorsBruce McConnell, Louise Kristine Vigsnæs, David Paul Kronlage
Life of this patent
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Abstract
The invention relates to a synthetic composition comprising human milk oligosaccharides for use in at least partially restoring the commensal gastrointestinal microbiota and preventing or mitigating antibiotic associated diarrhoea.
Claims12
A method for treating or reducing risk of a disorder associated with antibiotic therapy comprising
- administering daily to a human in need thereof at least 2 g of a mixture consisting of 2′-FL and LNnT, wherein the ratio of 2′-FL and LNnT is from about 1.5:1 to about 5:1 by weight
- wherein the disorder associated with antibiotic therapy is selected from the group consisting of diarrhoea, dysbiosis of the lower gastro-intestinal tract, and primary or recurrent Clostridium difficile infection, and wherein the human is undergoing or had previously undergone antibiotic therapy.
Dependencies are inferred from the claim text.