Applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products
AssigneeShanghai Jiao Tong University
InventorsYongyong Shi, Zhijian Song
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AssigneeShanghai Jiao Tong University
InventorsYongyong Shi, Zhijian Song
Estimating the term…
This invention discloses applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products. This invention provides applications for desogestrel in the preparation of products to treat colon cancer and/or breast cancer. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug desogestrel, experiments for this invention show, based on screening of non-anti-cancer drugs for various cancer cell lines (tissue types) and mutation sites, that desogestrel has a new use as an anti-colon cancer medication, thus achieving a new purpose for an old drug.
A method for treating Dukes type C colorectal adenocarcinoma in a subject comprising administering an effective amount of desogestrel to the subject.
A method of inhibiting the proliferation of Dukes type C colorectal adenocarcinoma cells comprising contacting the cells with an effective amount of desogestrel.
A method for treating a colon cancer patient with Dukes type C colorectal adenocarcinoma, the method comprising:
Dependencies are inferred from the claim text.