Composition and combined medication method for treating enterovirus infection

A composition for inhibiting enterovirus, wherein the composition includes a first active ingredient and a second active ingredient,

• wherein the first active ingredient is an inhibitor of 3C protein of enterovirus (eg, EV71);
• the second active ingredient is an inhibitor of 3A protein of enterovirus (eg, EV71);
• wherein the inhibitor of 3C protein of enterovirus (eg, EV71) is rupintrivir, an analog thereof, or a pharmaceutically acceptable salt thereof;
• and
• the inhibitor of 3A protein of enterovirus (eg, EV71) is itraconazole, an analog thereof, or a pharmaceutically acceptable salt thereof, and
• wherein a molar ratio of the first active ingredient to the second active ingredient is about 1-20:10-100.