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AssigneeRoche Diagnostics Operations, Inc.
InventorsEwelina Hegel, Hans-Peter Josel, Eloisa Lopez-Calle, Josef Roedl, Noah Weiss, Benjamin Tiemann
Estimating the term…
The present description relates to a liquid composition having at least one immune-modulatory macrolide compound and an essentially cell-free blood hemolysate. The present description further relates to a method for manufacturing a stabilized immune-modulatory macrolide calibration solution, by a) preparing a solution comprising an essentially cell-free blood hemolysate, b) admixing a predetermined amount of at least one immune-modulatory macrolide into said solution comprising an essentially cell-free blood hemolysate, and, thereby c) manufacturing a stabilized immune-modulatory macrolide calibration solution. Furthermore, the present description relates to kits, uses, devices, methods and to an immune-modulatory macrolide compound calibration solution related thereto.
A liquid composition comprising at least one immune-modulatory macrolide compound and an essentially cell-free blood hemolysate, wherein said immune-modulatory macrolide is at least one immune-modulatory macrolide selected from the group consisting of everolimus, sirolimus, tacrolimus, pimecrolimus and temsirolimus, and wherein essentially cell free is a number of less than 10 viable cells/ml.
A method for manufacturing a stabilized immune-modulatory macrolide calibration solution, comprising
Dependencies are inferred from the claim text.