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US 10,864,195 B2Granted
Topical localized isoxazoline formulation
AssigneeIntervet Inc.
InventorsStefan Fuchs, Anja Regina Heckeroth, Ramona Müller, Heike Williams, Hartmut Zoller
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Abstract
This invention provides topical localized formulations comprising an isoxazoline compound and a pharmaceutically or veterinary acceptable liquid carrier vehicle comprising N,N-diethyl-3-methylbenzamide as a solvent and an improved method for controlling, and preventing parasite infestation in animals.
Claims15
A topical localized formulation for the treatment of parasite infestation in animals which comprises an effective amount of at least one isoxazoline compound of the Formula (I)
- wherein
- R1 is 3-CF3, and 5-C1;
- n is 2;
- R2 is CF3;
- T is
- Q is X-NR3R4;
- X is C(O);
- R3 is -CH2-C(O)-NH-CH2-CF3;
- and R4 is H
- or
- R1 is 3-, 4-, and 5-Cl;
- n is 3;
- R2 is CF3;
- T is
- Q is X-NR3 R4;
- X is C(O);
- Y is methyl;
- R3 is -CH2-C(O)-NH-CH2-CF3;
- and R4 is H;
- and a veterinary acceptable liquid carrier vehicle wherein the liquid carrier vehicle comprises N,N-diethyl-3-methylbenzamide as a solvent.
17 more elements
Dependencies are inferred from the claim text.