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US 10,864,191 B2Granted
5-HT6 receptor antagonists for use in the treatment of Alzheimer's disease with apathy as comorbidity
AssigneeH. Lundbeck A/S
InventorKarl Tomas Odergren
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Abstract
The present invention relates to 5-HT6 receptor antagonists for the treatment of Alzheimer's disease with comorbid apathy comprising administering an effective dose of a 5-HT6 receptor antagonist to improve or augment the effect of an acetylcholinesterase inhibitor.
Claims15
A method for improving activities of daily living in a subject with Alzheimer's Disease and comorbid apathy, comprising administration of (i) a therapeutically effective amount of a 5HT6 receptor antagonist or pharmaceutically acceptable salt thereof, and (ii) an acetylcholinesterase inhibitor or a pharmaceutically acceptable salt thereof to said subject.
Dependencies are inferred from the claim text.