Method of synthesising sulforaphane
AssigneePharmAgra Labs, Inc.
InventorsSahadeva Reddy Damireddi, Kpakpo Ambrioise Akue, Jared K. Nelson, Albert Roger Frisbee, Peter Wyatt Newsome
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Abstract
The present invention relates to a method of synthesising sulforaphane by reacting a compound of formula (A) with an oxidizing agent in an aqueous solvent and in the presence of a catalyst. The invention further provides a method of synthesising a stabilised complex of sulforaphane and cyclodextrin by mixing the sulforaphane prepared by the methodology defined herein with cyclodextrin in an aqueous solvent.
Claims15
A complex of sulforaphane and alpha-cyclodextrin, which has a molar ratio of sulforaphane to alpha-cyclodextrin within the range 0.95:1 to 1:1, and wherein the complex has a purity as determined by HPLC of greater than 98%.
Dependencies are inferred from the claim text.