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AssigneesIndustry-Academic Cooperation Foundation, Yonsei University, National Cancer Center
InventorsJae Ho Cheong, Soo Youl Kim
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The present invention relates to a pharmaceutical composition for treating cancer, containing a polyphenol compound as an active ingredient. The pharmaceutical composition according to the present study is very effective for the treatment and prognosis-improvement of cancer stem cells or cancer tissues having a magnitude of cancer stem cells such as poorly differentiated cancer. Further, the polyphenol compound and a biguanide compound, and an anticancer agent were observed to remarkably increase inhibitory effects on the growth of cancerous cells when they were administered to cancerous cells in combination rather than individually, thus the composition is expected to find great applications in the cancer therapy field.
A method for preventing or treating stomach cancer, comprising administering to a subject in need of such treatment with an effective amount of a pharmaceutical composition which contains gossypol, phenformin, and irinotecan as active ingredients.
Dependencies are inferred from the claim text.