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US 10,864,152 B2Granted
TRPV3 agonists for the treatment of skin conditions
AssigneeSoricimed Biopharma Inc.
InventorJohn M. Stewart
Life of this patent
Estimating the term…
Abstract
Described are methods and uses of TRPV3 agonists for the treatment of conditions associated with TRPV3 pathophysiology such as acne, psoriasis, dermatitis, would healing, the inhibition of hair growth, anxiety or depression. Peptides comprising all or part of the C-terminal portion of soricidin are shown to activate TRPV3 cation channel activity and/or promote wound healing in keratinocytes.
Claims6
A method of promoting skin repair in a subject in need thereof comprising administering a topical formulation comprising a peptide consisting of 7, 8, or 9 contiguous amino acids of SEQ ID NO:
- 4 and an emollient to the skin of the subject in an amount that promotes the migration and/or proliferation of keratinocytes in the skin.
Dependencies are inferred from the claim text.