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US 10,770,197 B2Granted
Polymer-silica hybrid Pdots and methods of use thereof
AssigneeUniversity of Washington
InventorsDaniel T. Chiu, Jiangbo Yu, Yu Rong, Changfeng Wu
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Abstract
The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
Claims28
An organic-inorganic hybrid polymer dot comprising:
- a semiconducting chromophoric polymer;
- and
- an inorganic network,
- wherein the semiconducting chromophoric polymer and the inorganic network form an organic-inorganic interpenetrated network through physical association of the semiconducting chromophoric polymer and the inorganic network, and
- wherein the physical association of the semiconducting chromophoric polymer and the inorganic network does not include covalent bonding between the semiconducting chromophoric polymer and the inorganic network.
2 more elements
A method of making an organic-inorganic hybrid polymer dot, the method comprising:
- providing a solution, wherein the solution comprises a solvent, a semiconducting chromophoric polymer, and an organo-silane;
- and
- mixing the solution with an aqueous solution thereby forming an inorganic network,
- wherein at least one of the solution or the aqueous solution comprises an organo-silane comprising X, and wherein X is a functional group suitable for bioconjugation,
- wherein the semiconducting chromophoric polymer and the inorganic network form an organic-inorganic interpenetrated network through physical association of the semiconducting chromophoric polymer and the inorganic network, and
- wherein the physical association of the semiconducting chromophoric polymer and the inorganic network does not include covalent bonding between the semiconducting chromophoric polymer and the inorganic network.
3 more elements
Dependencies are inferred from the claim text.