Imaging systems and methods of using the same
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsAntonio C. Sobieranski, Utkan Demirci, Huseyin C. Tekin, Fatih Inci
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Abstract
Method and system for lensless, shadow optical imaging. Formation of a hologram shadow image having higher spatial resolution and lower noise level is accomplished by processing image information contained in multiple individual hologram shadow image frames acquired either under conditions of relative shift between point light source and the detector of the system or under stationary conditions, when system remains fixed in space and is devoid of any relative movement during the process of acquisition of individual image frames.
Claims10
A shadow optical imaging method comprising:
- receiving, at a single detector of a lensless optical imaging system, an optical shadow cast thereon by an object disposed in immediate proximity to said single detector and irradiated with a single diverging monochromatic wavefront of light produced by a light source,
- wherein said wavefront of light has an axis;
- acquiring multiple sets of optical data with said single detector over a period of time, each set of optical data representing a respectively-corresponding first image of said optical shadow formed with said wavefront at a respectively-corresponding point in time within said period in absence of a relative movement of any of the light source, the object, and the single detector along the axis,
- wherein a first spatial position of at least one of said detector, said object, and said light source is different from a second spatial position of at least one of said detector, said object, and said light source, the first spatial position defined at a first point in time within said period, the second spatial position defined at a second point in time within said period;
- wherein said first image is characterized by first spatial resolution;
- from said multiple sets of optical data, forming a second image of said object with a computer processor by minimizing a cost-function that at least partially represents a degree of blurring of each first image,
- wherein said second image is characterized by second spatial resolution, the second spatial resolution being higher than the first spatial resolution.
A shadow optical imaging method comprising:
- receiving, at a single detector of a lensless optical imaging system, an optical shadow cast thereon by an object that is disposed in immediate proximity to said single detector and that is irradiated with a single diverging monochromatic wavefront of light produced by a light source,
- wherein said wavefront of light has an axis;
- acquiring multiple sets of optical data with said single detector over a period of time, each set of optical data representing a respectively-corresponding first image of said optical shadow formed with said wavefront at a respectively-corresponding point in time within said period in absence of a relative movement of any of the light source, the object, and the single detector along the axis,
- wherein said wavefront has a rate of spatial divergence that remains unchanged in time and an optical axis the spatial orientation of which remains unchanged during said period of time,
- wherein said first image is characterized by a first spatial resolution;
- from said multiple sets of optical data, forming a second image of said object with a computer processor, said forming including anisotropic filtering of a set of optical data from said multiple sets to correct geometrical information of each first image.
Dependencies are inferred from the claim text.