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US 10,768,105 B1Granted
Image analysis and measurement of biological samples
AssigneeLabrador Diagnostics LLC
InventorsKaran Mohan, Chinmay Pangarkar
Life of this patent
Estimating the term…
Abstract
Methods, devices, apparatus, and systems are provided for image analysis. Methods of image analysis may include observation, measurement, and analysis of images of biological and other samples; devices, apparatus, and systems provided herein are useful for observation, measurement, and analysis of images of such samples. The methods, devices, apparatus, and systems disclosed herein provide advantages over other methods, devices, apparatus, and systems.
Claims21
A system for imaging a sample in a sample holder, comprising:
- a movable stage having a cavity for receiving the sample holder
- a light source for illuminating the sample held within said sample holder, said light source directing light within a first plane,
- an objective lens configured to collect and focus scattered light from said sample held within said sample holder, wherein said scattered light comprises light scattered at a plurality of scatter angles,
- a ring light mounted coaxially about a center axis of the objective lens;
- an angled reflective surface for directing light from the light source in a direction outward from said first plane towards said objective lens;
- a color wheel of filters for passing light from said objective lens, and
- a further lens configured to focus light from said objective lens onto an optical aperture,
- wherein the color wheel of filters is aligned in a first plane and the ring light is aligned in a second plane orthogonal to the first plane;
- wherein the movable stage is aligned in a third plane parallel to the first plane.
6 more elements
A system for imaging a sample in a sample holder, comprising:
- a movable stage having a cavity for receiving the sample holder
- a light source for illuminating the sample held within said sample holder, said light source directing light within a first plane,
- an objective lens configured to collect and focus scattered light from said sample held within said sample holder, wherein said scattered light comprises light scattered at a plurality of scatter angles,
- a ring light mounted coaxially about a center axis of the objective lens;
- an angled reflective surface for directing light from the light source in a direction outward from said first plane towards said objective lens;
- a color wheel of filters for passing light from said objective lens, and
- a further lens configured to focus light from said objective lens onto an optical aperture,
- wherein the color wheel of filters is aligned in a first plane and the ring light is aligned in a second plane orthogonal to the first plane;
- wherein the movable stage is aligned in a third plane parallel to the first plane;
- wherein the light source and the objective lens are both on one side of the movable stage.
7 more elements
A system for imaging a sample in a sample holder, comprising:
- a movable stage having a cavity for receiving the sample holder
- a light source for illuminating the sample held within said sample holder, said light source directing light within a first plane,
- an objective lens configured to collect and focus scattered light from said sample held within said sample holder, wherein said scattered light comprises light scattered at a plurality of scatter angles,
- a ring light mounted coaxially about a center axis of the objective lens;
- an angled reflective surface for directing light from the light source in a direction outward from said first plane towards said objective lens;
- a color wheel of filters for passing light from said objective lens, and a further lens configured to focus light from said objective lens onto said optical aperture,
- wherein the color wheel of filters is aligned in a first plane and the ring light is aligned in a second plane orthogonal to the first plane;
- wherein the movable stage is aligned in a third plane parallel to the first plane;
- wherein the sample holder comprises one or more optically non-transmissive surfaces.
6 more elements
Dependencies are inferred from the claim text.