Enzymatic preparation of Propamocarb
AssigneeEastman Chemical Company
InventorsStephanie Kay Clendennen, Neil Warren Boaz, Jean-Michel Rabasse
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Abstract
A process for preparing Propamocarb is presented. The preparation of Propamocarb (propyl 3-(dimethylamino)propylcarbamate) from 3-dimethylaminopropylamine and dipropyl carbonate is performed using an enzyme catalyst. In certain embodiments, the catalyst is a lipase enzyme, immobilized on a solid support. Advantages of the process include the avoidance of the use of chloroformate or vinyl carbonate.
Claims7
A process for preparing propyl-3-(dimethylamino)propylcarbamate comprising contacting dipropylcarbonate with 3-dimethylaminopropylamine in the presence of at least one enzymatic catalyst, wherein said catalyst comprises a lipase enzyme.
Dependencies are inferred from the claim text.