Temperature controlling surfaces and support structures

A heat exchange module for use in a chemical, pharmaceutical or biological reactor system, comprising:

• a vessel having an inner surface defining a chamber configured for supporting a replaceable or single use reactant container within the chamber, and an outer surface;
• a jacket at least partially encompassing the vessel, the jacket and the outer surface of the vessel defining a fluid circulation path therebetween through which a heat exchange fluid can be circulated;
• a plurality of baffles protruding from the inner surface of the vessel into the chamber;
• at least one of the plurality of baffles is hollow such that the heat exchange fluid can be circulated through the at least one baffle;
• and
• wherein at least one baffle of the plurality of baffles provides a thermally conductive surface adapted to contact the replaceable or single use reactant container to facilitate heat transfer.