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US 10,766,951 B2Granted
Antibodies against infectious diseases
AssigneeTaipei Medical University
InventorsSy-Jye Leu, Yi-Yuan Yang, Yu-Ching Lee, Ching-Hua Su, Ko-Jiunn Liu, Hsiu-Jung Lo, Yun-Liang Yang
Life of this patent
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Abstract
Anti-CaENO1 antibodies and humanized antibodies are provided as an effective diagnostic agent or a therapeutic treatment against infections caused by Candida spp., preferably Candida albicans, Candida tropicalis, fluconazole resistance Candida spp., Streptococcus, Staphylococcus.
Claims5
An isolated anti-CaENO1 antibody or an antigen-binding portion thereof, comprising a light chain complementarity determining region 1 (L-CDR1) of SEQ ID NO:5;
- a light chain CDR2 (L-CDR2) of SEQ ID NO:6;
- and a light chain CDR3 (L-CDR3) of SEQ ID NO:7;
- and a heavy chain CDR1 (H-CDR1) of SEQ ID NO:8;
- a heavy chain CDR2 (H-CDR2) of SEQ ID NO:9;
- and a heavy chain CDR3 (H-CDR3) of SEQ ID NO:10;
- such that said isolated antibody or antigen-binding portion thereof binds to CaENO1.
3 more elements
Dependencies are inferred from the claim text.