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US 10,766,859 B2Granted
Catalytic hydrogenation of nitriles
AssigneeBayer CropScience AG
InventorsWahed Ahmed Moradi, Thomas Himmler, Thomas Norbert Mueller
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Abstract
The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of Raney catalysts, in particular Raney nickel or cobalt.
Claims2
A process for preparing 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine or corresponding salts thereof,
- comprising
- (A1) hydrogenating [3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile in the presence of Raney cobalt catalyst.
Dependencies are inferred from the claim text.