US 10,765,892 B1 · Systems and methods for optimizing transcranial ultrasound focusing

Abstract

Systems and methods for predicting a phase correction of ultrasound waves transmitted from one or more transducer elements and traversing a patient's skull into a target region utilizing data of the patient's skull include predicting a first beam path of the ultrasound waves traversing the skull based at least in part on the target location; computationally determining structural characteristics of the skull along the first beam path based on the acquired imaging data; and predicting a second beam path of the ultrasound waves traversing the skull based at least in part on the determined structural characteristics, thereby accounting for refraction resulting from the skull.

Claims46

Dependent claims

A method of transmitting ultrasound waves from at least one transducer element and traversing a patient's skull into a target region utilizing data of the patient's skull, the method comprising:

(a) predicting a first beam path of the ultrasound waves traversing the skull into the target region based at least in part on a location of the target region;
(b) computationally determining structural characteristics of the skull along the first beam path based on the skull data;
(c) predicting a second beam path of the ultrasound waves traversing the skull based at least in part on the determined structural characteristics;
(d) updating the second beam path of the ultrasound waves based at least in part on at least one of a deviation between the second beam path and the location of the target region or the second beam path;
and
(e) activating the at least one transducer element in accordance with a treatment protocol.

3 more elements

Dependencies are inferred from the claim text.

Systems and methods for optimizing transcranial ultrasound focusing

Life of this patent

Systems and methods for optimizing transcranial ultrasound focusing

Life of this patent

Abstract

Claims46