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US 10,765,867 B2Granted
Transvascular nerve stimulation apparatus and methods
AssigneeLungpacer Medical Inc.
InventorJoaquin Andres Hoffer
Life of this patent
Estimating the term…
Abstract
Methods of stimulating a nerve may include inserting a lead structure into one or more blood vessels. The lead structure may include an insulating member, first electrodes and second electrodes supported on the insulating member, and at least one metal lead. The first electrodes and second electrodes may be positioned in one or more blood vessels. The methods of stimulating a nerve may further include the lead structures being applied to stimulate nerves such as the phrenic, vagus, trigeminal, obturator or other nerves.
Claims28
A method of stimulating at least one nerve, the method comprising:
- inserting a lead structure into one or more blood vessels, the lead structure to receive stimulation signals from a signal generator outside of a body having the blood vessel, wherein the lead structure includes an insulating member, first electrodes and second electrodes supported on the insulating member, and one or more metal leads surrounded by the insulating member;
- positioning the first electrodes in the one or more blood vessels and proximate a right phrenic nerve;
- positioning the second electrodes in the one or more blood vessels and proximate a left phrenic nerve;
- and
- during inspiration, stimulating at least one of the left phrenic nerve and the right phrenic nerve, via one or more electrodes of the first electrodes and the second electrodes in the one or more blood vessels, to assist in contracting a diaphragm;
- wherein positioning the first electrodes includes positioning at least two electrodes along a line generally parallel to the right phrenic nerve, and positioning the second electrodes includes positioning at least two electrodes along a line generally parallel to the left phrenic nerve.
3 more elements
A method of stimulating at least one nerve, the method comprising:
- positioning a first electrode array having two or more first electrodes in a first blood vessel;
- positioning a second electrode array having two or more second electrodes in a second blood vessel, said first and second electrode arrays arranged to receive stimulation signals from a signal generator outside of a body having the first and second blood vessels;
- selecting at least one of the first electrodes proximate a right phrenic nerve;
- selecting at least one of the second electrodes proximate a left phrenic nerve;
- and
- stimulating the first electrodes in the first blood vessel and the second electrodes in the second blood vessel, to assist in contracting a diaphragms wherein the first electrode array and the second electrode array are supported on an insulating member;
- and
- wherein positioning the first electrode array includes positioning at least two first electrodes along a line generally parallel to the right phrenic nerve, and positioning the second electrode array includes positioning a least two second electrodes along a line generally parallel to the left phrenic nerve.
5 more elements
A method of stimulating at least one nerve, the method comprising:
- inserting a lead structure into one or more blood vessels, the lead structure to receive stimulation signals from a signal generator outside of a body having the blood vessel, wherein the lead structure includes first electrodes and second electrodes;
- positioning the first electrodes in the one or more blood vessels and proximate a right phrenic nerve;
- positioning the second electrodes in the one or more blood vessels and proximate a left phrenic nerve;
- and
- during inspiration, stimulating at least one of the left phrenic nerve and the right phrenic nerve, via one or more electrodes of the first electrodes and the second electrodes in the one or more blood vessels, to assist in contracting a diaphragm;
- wherein the stimulating step does not occur during expiration.
3 more elements
A method of stimulating at least one nerve, the method comprising:
- positioning a first electrode array having two or more first electrodes in a first blood vessel;
- positioning a second electrode array having two or more second electrodes in a second blood vessel, said first and second electrode arrays arranged to receive stimulation signals from a signal generator outside of a body having the first and second blood vessels;
- selecting at least one of the first electrodes proximate a right phrenic nerve;
- selecting at least one of the second electrodes proximate a left phrenic nerve;
- and
- stimulating the first electrodes in the first blood vessel and the second electrodes in the second blood vessel, to assist in contracting a diaphragm;
- wherein the stimulating step does not occur during expiration.
4 more elements
Dependencies are inferred from the claim text.