Systems and methods for using a transcutaneous electrical stimulation device to deliver titrated therapy

A method of enabling a patient to achieve a weight loss objective using an electrical dermal patch secured to the patient's skin comprising a housing, an electrical pulse generator positioned within the housing, and at least one electrode attached to said housing and in electrical communication with the electrical pulse generator, wherein said electrical pulse generator is configured to deliver electrical pulses having a pulse amplitude in a range of 1 mA to 65 mA, the method comprising:

• using a plurality of programmatic instructions configured to execute on a device external to the electrical dermal patch, receiving data indicative of at least one of weight, well-being, hunger, appetite, calories consumed by the patient, or calories expended by the patient;
• applying a plurality of stimulation sessions to the patient's skin using said electrical dermal patch over a duration of one week, wherein each of the plurality of stimulation sessions comprises said electrical pulses, wherein at least some of the plurality of stimulation sessions have a duration of at least 15 minutes, and wherein the plurality of stimulation sessions comprises at least two in said week;
• repeatedly applying said plurality of stimulation sessions, wherein none of the plurality of stimulation sessions has a duration for more than 12 hours and has a pulse amplitude greater than 45 mAmp;
• and
• after a trigger, using the plurality of programmatic instructions configured to execute on the device external to the electrical dermal patch to modify said plurality of stimulation sessions based on at least one of the data indicative of weight, the data indicative of well-being, the data indicative of hunger, the data indicative of appetite, the data indicative of calories consumed by the patient, or the data indicative of calories expended by the patient.

A method of enabling a patient to achieve a weight loss objective using an electrical dermal patch secured to the patient's skin comprising a housing, an electrical pulse generator positioned within the housing, and at least one electrode attached to said housing and in electrical communication with the electrical pulse generator, wherein said electrical pulse generator is configured to deliver electrical pulses having a pulse amplitude in a range of 1 mA to 65 mA, the method comprising:

• using a plurality of programmatic instructions configured to execute on a device external to the electrical dermal patch, receiving data indicative of at least one of weight, well-being, hunger, appetite, calories consumed by the patient, or calories expended by the patient and further receiving data indicative of a weight loss goal;
• applying a plurality of stimulation sessions to the patient's skin using said electrical dermal patch over a duration of one week, wherein each of the plurality of stimulation sessions comprises said electrical pulses, wherein at least some of the plurality of stimulation sessions have a duration of at least 15 minutes, and wherein the plurality of stimulation sessions comprises at least two in the week;
• repeatedly applying said plurality of stimulation sessions over a predefined period of time;
• and
• after the predefined period of time, using the plurality of programmatic instructions configured to execute on the device external to the electrical dermal patch to modify said plurality of stimulation sessions based on at least one of the data indicative of weight, the data indicative of well-being, the data indicative of hunger, the data indicative of appetite, the data indicative of calories consumed by the patient, or the data indicative of calories expended by the patient.

A method of enabling a patient to achieve a weight loss objective using an electrical dermal patch secured to the patient's skin comprising a housing, an electrical pulse generator positioned within the housing, and at least one electrode attached to said housing and in electrical communication with the electrical pulse generator, wherein said electrical pulse generator is configured to deliver electrical pulses having a pulse amplitude in a range of 1 mA to 65 mA, a pulse width in a range of 10 μsec to 10 msec and a pulse frequency in a range of 1 Hz to 100 Hz, the method comprising:

• using a plurality of programmatic instructions configured to execute on a device external to the electrical dermal patch, receiving data indicative of at least one of weight, well-being, hunger, appetite, calories consumed by the patient, or calories expended by the patient;
• applying a plurality of stimulation sessions to the patient's skin using said electrical dermal patch over a duration of one week, wherein each of the plurality of stimulation sessions comprises said electrical pulses, wherein each of said electrical pulses is defined by a plurality of stimulation parameters, wherein at least some of the plurality of stimulation sessions have a duration of at least 15 minutes, and wherein the plurality of stimulation sessions comprises at least two in the week;
• repeatedly applying said plurality of stimulation sessions over a predefined period of time;
• and
• after the predefined period of time, using the plurality of programmatic instructions configured to execute on the device external to the electrical dermal patch to modify said plurality of stimulation sessions based on at least one of the data indicative of weight, the data indicative of well-being, the data indicative of hunger, the data indicative of appetite, the data indicative of calories consumed by the patient, or the data indicative of calories expended by the patient.

A method of enabling a patient to achieve a weight loss objective using an electrical dermal patch secured to the patient's skin comprising a housing, an electrical pulse generator positioned within the housing, and at least one electrode attached to said housing and in electrical communication with the electrical pulse generator, wherein said electrical pulse generator is configured to deliver electrical pulses having a pulse amplitude in a range of 1 mA to 65 mA, the method comprising:

• using a plurality of programmatic instructions configured to execute on a device external to the electrical dermal patch, receiving data indicative of at least one of weight, well-being, hunger, appetite, calories consumed by the patient, or calories expended by the patient;
• applying a plurality of stimulation sessions to the patient's skin using said electrical dermal patch over a duration of one week, wherein each of the plurality of stimulation sessions comprises said electrical pulses, wherein at least some of the plurality of stimulation sessions have a duration of at least 15 minutes, wherein the plurality of stimulation sessions comprises at least two in the week, wherein a total energy delivered by the plurality of stimulation sessions applied over the one week is not less than 0.25 joules and wherein a total energy delivered by one of said plurality of stimulation sessions does not exceed 6 joules;
• repeatedly applying said plurality of stimulation sessions over a predefined period of time;
• and
• after the predefined period of time, using the plurality of programmatic instructions configured to execute on the device external to the electrical dermal patch to modify said plurality of stimulation sessions based on at least one of the data indicative of weight, the data indicative of well-being, the data indicative of hunger, the data indicative of appetite, the data indicative of calories consumed by the patient, or the data indicative of calories expended by the patient.

A method of enabling a patient to achieve a weight loss objective using an electrical dermal patch secured to the patient's skin comprising a housing, an electrical pulse generator positioned within the housing, and at least one electrode attached to said housing and in electrical communication with the electrical pulse generator, wherein said electrical pulse generator is configured to deliver electrical pulses having a pulse amplitude in a range of 1 mA to 65 mA, the method comprising:

• using a plurality of programmatic instructions configured to execute on a device external to the electrical dermal patch, receiving data indicative of at least one of weight, well-being, hunger, appetite, calories consumed by the patient, or calories expended by the patient;
• generating, via the electrical dermal patch, at least one of a visual, auditory, or vibratory signal to the patient within 30 minutes before initiating one of said plurality of stimulation sessions;
• applying a plurality of stimulation sessions to the patient's skin using said electrical dermal patch over a duration of one week, wherein each of the plurality of stimulation sessions comprises said electrical pulses, wherein at least some of the plurality of stimulation sessions have a duration of at least 15 minutes, and wherein the plurality of stimulation sessions comprises at least two occurring on different days in the week;
• repeatedly applying said plurality of stimulation sessions over a predefined period of time;
• and
• after the predefined period of time, using the plurality of programmatic instructions configured to execute on the device external to the electrical dermal patch to modify said plurality of stimulation sessions based on at least one of the data indicative of weight, the data indicative of well-being, the data indicative of hunger, the data indicative of appetite, the data indicative of calories consumed by the patient, or the data indicative of calories expended by the patient.

A method of enabling a patient to achieve a weight loss objective using an electrical dermal patch secured to the patient's skin comprising a housing, an electrical pulse generator positioned within the housing, and at least one electrode attached to said housing and in electrical communication with the electrical pulse generator, wherein said electrical pulse generator is configured to deliver electrical pulses having a pulse amplitude in a range of 1 mA to 65 mA, the method comprising:

• using a plurality of programmatic instructions configured to execute on a device external to the electrical dermal patch, receiving data indicative of at least one of weight, well-being, hunger, appetite, calories consumed by the patient, or calories expended by the patient;
• applying a plurality of stimulation sessions to the patient's skin using said electrical dermal patch over a duration of one week, wherein each of the plurality of stimulation sessions comprises said electrical pulses, wherein at least some of the plurality of stimulation sessions have a duration of at least 15 minutes, and wherein the plurality of stimulation sessions comprises at least two in the week;
• repeatedly applying said plurality of stimulation sessions over a predefined period of time, wherein at least a portion of said plurality of stimulation sessions are applied between 6 am and 9 am, between 11 am and 2 pm or between 5 pm and 9 pm;
• and
• after the predefined period of time, using the plurality of programmatic instructions configured to execute on the device external to the electrical dermal patch to modify said plurality of stimulation sessions based on at least one of the data indicative of weight, the data indicative of well-being, the data indicative of hunger, the data indicative of appetite, the data indicative of calories consumed by the patient, or the data indicative of calories expended by the patient.