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US 10,765,829 B2Granted
Delivery of gases to the nasal airway
AssigneeOptiNose AS
InventorsPer Gisle Djupesland, Roderick Peter Hafner
Life of this patent
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Abstract
A delivery device for and a method of delivering gases to the nasal airway, in particular therapeutic gases and gases in combination with active substances, either as powders or liquids, for enhanced uptake of the active substances.
Claims24
A method of delivering an uptake enhancing gas and a substance to a nasal airway of a subject comprising:
- fitting a nosepiece into one nostril of the subject;
- fitting a mouthpiece into a mouth of the subject, the mouthpiece fluidly connected to the nosepiece and configured to permit the subject to cause a flow of exhaled breath through the mouthpiece and through the nosepiece;
- causing the substance to be delivered into the flow of exhaled breath;
- and
- causing the uptake enhancing gas to be delivered into the flow of exhaled breath;
- wherein the uptake enhancing gas is carbon dioxide.
3 more elements
A method of delivering an uptake enhancing gas and a substance to a nasal airway of a subject comprising:
- fitting a nosepiece into one nostril of the subject;
- fitting a mouthpiece into a mouth of the subject, the mouthpiece fluidly connected to the nosepiece and configured to permit the subject to cause a flow of exhaled breath through the mouthpiece and through the nosepiece;
- and
- causing the substance and the uptake enhancing gas to be delivered into the flow of exhaled breath;
- wherein the uptake enhancing gas is at least 10 vol. % of a combined flow of the flow of exhaled breath and the uptake enhancing gas.
2 more elements
Dependencies are inferred from the claim text.