System and method for dialyzer evaluation
AssigneeFresenius Medical Care Holdings, Inc.
InventorsLouis LeeGrande Barrett, Chih-Hu Ho, Eric Stroup
Life of this patent
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Abstract
Embodiments of the disclosure provide a method for evaluating dialyzers used in different medical applications (e.g., hemodialysis). Red blood cell volume lost in a dialyzer is monitored by obtaining blood flowrate measurements and hematocrit measurements at input ports and output ports of the dialyzer. The flowrate and hematocrit measurements are used to determine an accumulation of red cell blood volume in the dialyzer. The measurements may be obtained in a lab environment with an in-vitro blood source or may be obtained in a clinical setting with an in-vivo blood source from a patient.
Claims20
A dialyzer analysis system, comprising:
- a first sensor connected to a first portion of a blood flow path disposed on an input side of a dialyzer, wherein the first sensor is configured to obtain a measurement corresponding to hematocrit of blood in the first portion of the blood flow path;
- a second sensor connected to a second portion of the blood flow path disposed on an output side of the dialyzer, wherein the second sensor is configured to obtain a measurement corresponding to hematocrit of blood in the second portion of the blood flow path;
- and
- a controller configured to determine a red blood cell volume loss corresponding to an amount of red blood cells remaining in the dialyzer based on the measurements from the first and second sensors.
A method for dialyzer analysis, comprising:
- obtaining, by a first sensor of a dialyzer analysis system connected to a first portion of a blood flow path disposed on an input side of a dialyzer, a measurement corresponding to hematocrit of blood in the first portion of the blood flow path;
- obtaining, by a second sensor of the dialyzer analysis system connected to a second portion of the blood flow path disposed on an output side of the dialyzer, a measurement corresponding to hematocrit of blood in the second portion of the blood flow path;
- and
- determining, by a controller of the dialyzer analysis system, a red blood cell volume loss corresponding to an amount of red blood cells remaining in the dialyzer based on the measurements from the first and second sensors.
A non-transitory computer-readable medium having processor-executable instructions stored thereon for dialyzer analysis, the processor-executable instructions, when executed, facilitating:
- obtaining, by a first sensor of a dialyzer analysis system connected to a first portion of a blood flow path disposed on an input side of a dialyzer, a measurement corresponding to hematocrit of blood in the first portion of the blood flow path;
- obtaining, by a second sensor of the dialyzer analysis system connected to a second portion of the blood flow path disposed on an output side of the dialyzer, a measurement corresponding to hematocrit of blood in the second portion of the blood flow path;
- and
- determining, by a controller of the dialyzer analysis system, a red blood cell volume loss corresponding to an amount of red blood cells remaining in the dialyzer based on the measurements from the first and second sensors.
Dependencies are inferred from the claim text.