Detection of pump thrombosis

A pump thrombosis detection system comprising:

• a transducer configured to generate a signal representative of a mechanical wave from a mechanical circulatory support device, wherein the transducer is one of within or coupled to an implantable medical device remote from the mechanical circulatory support device;
• processing circuitry communicatively coupled to the transducer, wherein the processing circuitry is configured to:
• identify a first portion of the signal representative of at least one harmonic of the mechanical wave,
• normalize, based on a second portion of the signal, the first portion of the signal, and
• determine, based on the normalized first portion, an indication of pump thrombosis;
• and
• a user interface communicatively coupled to the processing circuitry, wherein the user interface is configured to alert a user of the indication of pump thrombosis.

A method of detecting pump thrombosis comprising:

• receiving, by processing circuitry communicatively coupled to a transducer, a signal representative of a mechanical wave generated by a mechanical circulatory support device;
• identifying, by the processing circuitry, a first portion of the signal representative of at least one harmonic of the mechanical wave;
• normalizing, by the processing circuitry, based on a second portion of the signal, the first portion;
• determining, by the processing circuitry, based on the normalized first portion, an indication of pump thrombosis;
• and
• based on the indication of the pump thrombosis, at least one of alerting, by a user interface communicatively coupled to the processing circuitry, a user of the indication of pump thrombosis or initiating an intervention.

A medical device system comprising:

• means to receive, by processing circuitry communicatively coupled to a transducer, a signal representative of a mechanical wave generated by a mechanical circulatory support device;
• means to identify, by the processing circuitry, a first portion of the signal representative of at least one harmonic of the mechanical wave,
• means to normalize, by the processing circuitry, based on a second portion of the signal, the first portion of the signal,
• means to determine, by the processing circuitry, based on the normalized first portion, an indication of pump thrombosis;
• and
• means to, based on the indication of the pump thrombosis, at least one of alert, by a user interface communicatively coupled to the processing circuitry, a user of the indication of pump thrombosis or initiate an intervention.

A non-transitory computer-readable storage medium comprising instructions that, when executed by processing circuitry of a medical device system, cause the processing circuitry to:

• receive, by the processing circuitry communicatively coupled to a transducer, a signal representative of a mechanical wave generated by a mechanical circulatory support device;
• identify a first portion of the signal representative of at least one harmonic of the mechanical wave;
• normalize, based on a second portion of the signal, the first portion;
• determine, based on the normalized first portion, an indication of pump thrombosis based on the signal;
• and
• based on the indication of the pump thrombosis, at least one of alert, by a user interface communicatively coupled to the processing circuitry, a user of the indication of pump thrombosis or initiate an intervention.