Treatment of disease with poly-N-acetylglucosamine nanofibers
AssigneeMarine Polymer Technologies, Inc.
InventorsJohn N. Vournakis, Sergio Finkielsztein
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Abstract
This application relates to compositions comprising shortened fibers of poly-N-acetylglucosamine and/or a derivative thereof (“sNAG nanofibers”) and the use of such compositions in the treatment of disease.
Claims37
A method for treating atopic dermatitis in a human subject, comprising topically administering a composition comprising shortened poly-N-acetylglucosamine fibers (“sNAG nanofibers”) to the skin of a human subject in need thereof, wherein the sNAG nanofibers comprise 70%, or more than 70%, of N-acetylglucosamine monosaccharides, wherein more than 50% of the sNAG nanofibers are between 1 to 15 μm in length, and wherein the sNAG nanofibers are the only active ingredient in the composition.
A method for reducing the severity or duration of one or more symptoms associated with atopic dermatitis in a human subject, comprising topically administering a composition comprising shortened poly-N-acetylglucosamine fibers (“sNAG nanofibers”) to the skin of a human subject in need thereof, wherein the sNAG nanofibers comprise 70%, or more than 70%, of N-acetylglucosamine monosaccharides, wherein more than 50% of the sNAG nanofibers are between 1 to 15 μm in length, and wherein the sNAG nanofibers are the only active ingredient in the composition.
A method for treating inflammatory bowel disease in a human subject, comprising topically administering a composition comprising shortened poly-N-acetylglucosamine fibers (“sNAG nanofibers”) to a human subject in need thereof, wherein the sNAG nanofibers comprise 70%, or more than 70%, of N-acetylglucosamine monosaccharides, wherein more than 50% of the sNAG nanofibers are between 1 to 15 μm in length, and wherein the sNAG nanofibers are the only active ingredient in the composition.
Dependencies are inferred from the claim text.