Methods and compounds to inhibit enveloped virus release
AssigneesNorthwestern University, The Research Foundation for The State University of New York
InventorsJonathan Leis, Carol Carter
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Abstract
A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.
Claims4
A method of treating an infection by an enveloped virus in a patient, the method consisting of administering to the patient a pharmaceutical composition consisting of a compound of a formula:
Dependencies are inferred from the claim text.