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US 10,765,640 B2Granted
Non-aqueous patch
AssigneesITOCHU CHEMICAL FRONTIER Corporation, Oishi Koseido Co., Ltd.
InventorsTatsuya Mori, Naoyuki Saida
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AssigneesITOCHU CHEMICAL FRONTIER Corporation, Oishi Koseido Co., Ltd.
InventorsTatsuya Mori, Naoyuki Saida
Estimating the term…
[Problem] If lidocaine is composed of non-aqueous patch, the adhesive power of the preparation tends to get lower, as the composition amount of lidocaine is higher. It is popular to solve lidocaine in dissolving agent in order to compose lidocaine in patch and release effective amount into skin. However, if the amount of dissolving agent gets higher, the adhesive power gets extremely lower, so that an long-time attachment is difficult. [Solution] A non-aqueous patch comprising lidocaine and/or its reactant, and a dissolving agent which are contained in a base of plaster, the plaster being hold by a support, of which strength of 50% stretched to longitudinal direction is less than 2,000 g/50 mm and of biaxially-oriented stretch cloth.
A non-aqueous patch comprising 0.5 to 7 mass % lidocaine, and a dissolving agent comprising an organic acid and a polyalcohol, wherein the lidocaine and the dissolving agent are in a plaster, the plaster being held by a support, wherein the support has a stretch strength of less than 2,000g/50 mm when the support is stretched by 50% longitudinal extension;
Dependencies are inferred from the claim text.